INBRE 2018 Workshops:
Saturday November 3, 10:30-11:45.
Workshop 1 – “Leveraging Public Sequence Databases with Next Generation Tools!”
Chemistry building, Room 144
Ben Busby, NIH/NLM/NCBI
This workshop will begin with a demonstration of new computational and visualization tools offered by NCBI and others in the bioinformatics community. Methods for extracting data from databases will also be demonstrated, particularly “edge computing,” or the practice of streaming data from where it is stored rather than downloading it, using magicBLAST as an example. We’ll also discuss other high-throughput ways to access data and metadata, such as the EDirect command line metadata API, taxonomic organization of SRA datasets, and online .bam visualization. We’ll also discuss how these data extraction mechanisms can be paired with community resources, and general frameworks such as Galaxy, CyVerse, Bioconda, and Bioconductor. Bringing a laptop computer is requested.
Workshop 2 – Preparing for Graduate School in Chemistry or Biology
Chemistry Building, Room 132
Colin Heyes, PhD, Department of Chemistry and Biochemistry, UAF
This workshop is targeted towards undergraduate students who are considering graduate school as a career. Topics to be discussed will include graduate school expectations and how to prepare for and select the right graduate school and program for you.
A panel of faculty and graduate students will be available to share their tips, strategies, insights, and practical advice. We conclude with a Question and Answer session, with the possibility of breaking out into smaller groups based on specific interests.
Workshop 3- Preparing for Graduate School in Physics
Physics Building, Room 132
Reeta Vyas, PhD, Professor of Physics, UAF
Limited to 20 participants
Participants will learn about career options for physics graduates, dos and don’ts of the application process for Physics Graduate Programs in the US – importance of and preparation for GRE, course work, recommendation letters, assistantships, etc.
Workshop 4 – Molecular Modeling
Chemistry Building, Room 308
Peter Pulay, PhD, Department of Chemistry and Biochemistry, UAF
Limited to 12 participants or groups. If feasible, bring a computer, although this is optional.
Methods of molecular modeling on a personal computer will be addressed, with software available for distribution to up to 12 individuals or cluster teams.
Workshop 5 – Nanochemistry
Chemistry Building, Room 147
Jingyi Chen, Department of Chemistry and Biochemistry, UAF
Limited to 15 participants
Description: Nanochemistry plays an important role in many applications ranging from medicines to catalysis, electronics, energy conversion and storage. In this workshop, the emphasis focuses on the nanochemistry in theranostics applications, in particular, the use of nanoparticles in disease diagnostics and therapy. An overview of nanomedicine will be presented, followed by a specific example based on the gold nanostructure nanoplatform.
Workshop 6 – A Beginner’s Workshop for Statistical Techniques for Medical Studies
Gearhart Hall, Room 101 (Computer Lab)
Zhuoxin Sun, Ph.D., Senior Statistician, ECOG-ACRIN Cancer Research Group and International Breast Cancer Study Group, Senior Research Scientist, Frontier Science and Technology, Adjunct Associate Professor, Math Dept, UAF
The workshop has a maximum enrollment of 20.
This workshop will begin with an introduction of some basic ideas about clinical trials in medical research. It will cover different types of clinical trials conducted at various stages of drug development, principles to avoid bias in clinical trials, and ideas about determining the number of patients needed in a clinical trial. Two hands-on case studies with clinical data will be examined to demonstrate how to use some basic statistical techniques in clinical trials. The hand-on exercises will be performed with Microsoft Excel with the Data Analysis Addin.
Workshop 7 – Cellular Mechanisms of Salt and Water Transport in Fish
Ferritor Building, Room 317
Christian Tipsmark, PhD, Biology Department, UAF
The goal of physiological research is to understand the function of living systems from the level of the whole organism and its organs to that of the single cells and bio-molecules. This workshop highlights mechanisms and regulation of salt and water transport in fish and demonstrates some of the methods used in physiology. It will cover experimentations with whole animals and isolated tissues. Techniques demonstrated will include enzyme assays, specific mRNA and protein quantification and cellular localization of specific proteins with immunofluorescence.
Workshop 8 – Physics “Super-Resolution Fluorescence Microscopy”
Physics Building, Room 133 and Room 115A
Yong Wang, PhD, Professor of Physics, UAF
Limited to 15 participants
This workshop will briefly introduce the basics of super-resolution fluorescence microscopy based on single-molecule localization, which improves the spatial resolution of light microscopy from ~300 nanometers to ~20 nanometers (see 2014 Nobel Prize in Chemistry for more details). Attendees will have a chance to image an important universal regulatory protein – HNS – in E. coli bacteria, to localize individual HNS molecules, and to produce super-resolved images of HNS proteins in E. coli with a resolution of ~20 nanometers.
Workshop 9 –Physics “High Temperature Superconductor”
Physics Building, Room 134 and Room 131
Jin Hu, PhD, Professor of Physics, UAF
Limited to 12 participants
The discovery of superconductivity is one of the major breakthroughs in Physics in the last century. The studies on superconductivity and related phenomena have been awarded several Nobel prizes. This workshop will introduce this fascinating quantum phenomenon. Workshop attendees will then have the opportunity to synthesize the high temperature superconductor.
Workshop 10 – Physics: “A 2D How-to”
Nano Building, Room 105
Hugh Churchill, PhD, Professor of Physics, UAF
Limited to 15 participants.
After a brief introduction to the field of 2D material research, I will demonstrate the now-famous “Scotch tape technique” that is used to peel apart atomically thin layers of graphene and many other 2D materials from 3D crystals. Workshop attendees will then have the opportunity to try this themselves using tape, tweezers, and silicon chips, followed by “flake hunting” with a microscope.
Workshop 11 – “Visualizing Mitochondrial Dynamics”
Ferritor Building Room 325
Shilpa Iyer, PhD, Assistant Professor of Biology, UA, Fayetteville
Limited to 10 participants.
The goal is to understand mitochondrial changes in healthy and diseased states. We will demonstrate techniques that will visualize and analyze acquired images from multiple cell types corresponding to different mitochondrial diseases.